Colon Cancer: Causes, Symptoms, Diagnosis, and Treatment | Prevention Tips
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October, 2024

Colon Cancer

Colon cancer, also known as colorectal cancer, develops in the large intestine (colon), which is part of the digestive system. It typically starts as small, benign growths called polyps that can, over time, turn into cancer. Colon cancer is one of the most common types of cancer, but the good news is that with early detection and treatment, it is highly treatable.

What Is Colon Cancer?

Colon cancer occurs when cells in the lining of the colon grow uncontrollably, forming a tumor. If left untreated, these cancerous cells can spread to other parts of the body. Most colon cancers begin as non-cancerous polyps. Regular screening can detect these polyps early and prevent cancer from developing.

Causes of Colon Cancer

The exact cause of colon cancer isn’t fully understood, but several factors increase the risk of developing the disease:
  • Age: Most cases of colon cancer occur in people over 50.
  • Genetics and Family History: A family history of colon cancer increases your risk, especially if relatives were diagnosed at a young age.
  • Lifestyle Factors: Poor diet (high in red or processed meats, low in fiber), lack of exercise, smoking, and excessive alcohol consumption are linked to a higher risk.
  • Chronic Conditions: Conditions like inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, can increase the likelihood of colon cancer.
  • Genetic Syndromes: Certain inherited conditions like Lynch syndrome and familial adenomatous polyposis (FAP) also elevate risk.

Symptoms of Colon Cancer

In the early stages, colon cancer may not cause any symptoms. However, as the disease progresses, you may experience:
  • Changes in Bowel Habits: Persistent diarrhea, constipation, or changes in stool consistency that last for more than a few days.
  • Blood in Stool: Bright red or dark, tarry stools may indicate bleeding in the colon.
  • Abdominal Discomfort: Cramping, pain, or bloating that does not go away.
  • Unexplained Weight Loss: Losing weight without trying can be a sign of many cancers, including colon cancer.
  • Fatigue: Feeling unusually tired or weak can be caused by the cancer's impact on nutrient absorption or internal bleeding.
  • Incomplete Bowel Movements: A feeling that the bowel doesn't empty completely after a movement.
If you notice any of these symptoms, especially for more than a few weeks, it’s important to consult a doctor.

Diagnosis of Colon Cancer

Diagnosing colon cancer involves several steps:
  • Screening Tests:
    • Colonoscopy: A flexible tube with a camera is inserted into the rectum to view the entire colon. Any suspicious polyps can be removed and tested for cancer.
    • Stool Tests: Tests like the fecal occult blood test (FOBT) or fecal immunochemical test (FIT) check for hidden blood in the stool.
  • Imaging Tests:
    • CT Scans: Used to get a detailed view of the colon and check if cancer has spread.
    • MRI and Ultrasound: These may be used to evaluate the extent of the cancer.
  • Biopsy: If a polyp or suspicious area is found, a small tissue sample is taken for laboratory testing to confirm if it is cancerous.

Stages of Colon Cancer

Colon cancer is divided into stages based on how far the cancer has spread:
  • Stage 0 (Carcinoma in Situ): Cancer is only in the innermost lining of the colon.
  • Stage I: Cancer has spread into the muscle layer of the colon.
  • Stage II: Cancer has spread through the outer layer of the colon but hasn’t reached nearby lymph nodes.
  • Stage III: Cancer has spread to nearby lymph nodes but not to other parts of the body.
  • Stage IV: Cancer has spread to distant organs, such as the liver or lungs.

Treatment of Colon Cancer

Treatment options for colon cancer depend on the stage of the disease, but common approaches include:
  • Surgery:
    • Polypectomy: If cancer is detected early, during a colonoscopy, polyps may be removed before they become malignant.
    • Partial Colectomy: For more advanced cases, a portion of the colon containing cancer may be surgically removed. In some cases, the healthy parts of the colon are reconnected.
    • Colostomy: In rare cases, if reconnecting the colon is not possible, a colostomy is performed to create an opening in the abdominal wall to pass waste.
  • Chemotherapy: Chemotherapy uses drugs to kill cancer cells or shrink tumors. It is often used after surgery to eliminate any remaining cancer cells or in advanced stages to slow the spread of the disease.
  • Radiation Therapy: Radiation uses high-energy rays to target and kill cancer cells. It is more commonly used in rectal cancer but may also be used for colon cancer, especially in later stages.
  • Targeted Therapy: This newer treatment targets specific molecules that cancer cells use to grow. Targeted therapies are often used when colon cancer has spread to other parts of the body.
  • Immunotherapy: Immunotherapy helps the immune system recognize and attack cancer cells. It is typically used for advanced colon cancer that does not respond to other treatments.

Prevention of Colon Cancer

While there is no sure way to prevent colon cancer, certain lifestyle changes and regular screenings can significantly reduce your risk:
  • Screening: Regular colonoscopies, especially after age 50, can detect polyps early and prevent them from turning into cancer.
  • Healthy Diet: Eating a diet rich in fruits, vegetables, and whole grains and reducing red and processed meats can lower your risk.
  • Exercise: Regular physical activity helps maintain a healthy weight, which can reduce your cancer risk.
  • Avoid Smoking and Excess Alcohol: Both smoking and excessive alcohol use are linked to higher risks of many cancers, including colon cancer.

Conclusion

Colon cancer is a common and potentially life-threatening disease, but with early detection and treatment, the outlook is often positive. Regular screenings, a healthy lifestyle, and being aware of the symptoms are essential steps in reducing your risk. If you experience any unusual changes in your bowel habits or notice other symptoms, consult a doctor for evaluation. Early intervention can save lives.

By taking care of your digestive health and staying proactive, you can significantly reduce the risk of colon cancer and enjoy a healthy, balanced life.

 

Doctor

Dr Amruthesh T.M

Senior Consultant - Gastroenterology & Hepatology
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